Canthaxanthin (Synonyms: 斑蝥黄; E 161g; all-trans-Canthaxanthin)

目录号: HY-B1960 纯度: ≥98.0%: FAQs
Data Sheet SDS COA 产品使用指南

摩尔计算器

Canthaxanthin是具有多种生物活性的红橙色类胡萝卜素，如抗氧化，抗肿瘤活性。

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Canthaxanthin Chemical Structure

CAS No. : 514-78-3

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规格	价格	是否有货
1 mg	￥457	In-stock
5 mg	￥1100	In-stock
10 mg	￥1800	In-stock
50 mg	￥5400	In-stock
100 mg	现货	询价
200 mg		询价
500 mg		询价

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Other Forms of Canthaxanthin:

Canthaxanthin (Standard) 询价

MCE 顾客使用本产品发表的 2 篇科研文献

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生物活性
实验参考方法
纯度 & 产品资料
参考文献

生物活性

Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.

IC₅₀ & Target

Human Endogenous Metabolite

体外研究
(In Vitro)

LDL 的 Canthaxanthin 富集具有保护胆固醇免于氧化的潜力。除了其自由基清除和抗氧化特性 (例如，过氧化氢酶和超氧化物歧化酶的诱导) 外，Canthaxanthin 还具有免疫调节活性 (例如增强免疫感受态细胞的增殖和功能) 并在缝隙连接通讯中发挥重要作用 (例如诱导跨膜蛋白连接蛋白)^[1]。在 0.1 到 1 x 1000 μM 的浓度下，Canthaxanthin 显著减少肿瘤细胞的总数。在孵育 72 小时和 96 小时后，在 Canthaxanthin 浓度为 1000 时观察到最大的抑制作用^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Canthaxanthin 改变组织对抗氧化应激的保护能力。Canthaxanthin 以 14 μg/kg 的剂量处理 15 天导致类胡萝卜素在肝脏中的掺入，在肝脏中含量最高，达到 0.52 ± 0.05 nmol/g。Canthaxanthin 处理小鼠的谷胱甘肽过氧化物酶活性比对照组低 35%，过氧化氢酶 (59%) 和锰超氧化物歧化酶 (28%) 活性高于对照组^[3]。Canthaxanthin 抑制小鼠乳腺肿瘤的生长，其抗肿瘤活性还受补充剂量的影响^[4]。通过一种不涉及维生素 A 原活性的机制，在摄入致癌物之前 3 周在饮食中补充 Canthaxanthin 可使乳腺癌的发病率降低 65%^[5]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

564.84

Formula

C₄₀H₅₂O₂

CAS 号

514-78-3

性状

固体

颜色

Reddish brown to black

中文名称

角黄素；斑蝥黄质；斑蝥黄；裸藻酮

结构分类

初始来源

动物

微生物

extremely halophilic bacteria

运输条件

Shipping with dry ice.

储存方式

-20°C, protect from light, stored under nitrogen

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。

溶解性数据

细胞实验：

Chloroform 中的溶解度 : 25 mg/mL (44.26 mM; 超声助溶)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.7704 mL	8.8521 mL	17.7041 mL
5 mM	0.3541 mL	1.7704 mL	3.5408 mL
10 mM	0.1770 mL	0.8852 mL	1.7704 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。

摩尔计算器
稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)

体积 _(start)

浓度 _(final)

体积 _(final)

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

计算结果

工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: ≥98.0%

选择批次：

Data Sheet (629 KB) SDS (393 KB)

COA (187 KB) HNMR (228 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Esatbeyoglu T, et al. Canthaxanthin: From molecule to function. Mol Nutr Food Res. 2017 Jun;61(6). [Content Brief]

[2]. Huang DS, et al. Inhibitory effects of canthaxanthin on in vitro growth of murine tumor cells. Cancer Lett. 1992 Aug 31;65(3):209-13. [Content Brief]

[3]. Palozza P, et al. Canthaxanthin supplementation alters antioxidant enzymes and iron concentration in liver of Balb/c mice. J Nutr. 2000 May;130(5):1303-8. [Content Brief]

[4]. Chew BP, et al. A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res. 1999 May-Jun;19(3A):1849-53. [Content Brief]

[5]. Grubbs CJ, et al. Effect of canthaxanthin on chemically induced mammary carcinogenesis. Oncology. 1991;48(3):239-45. [Content Brief]

Animal Administration ^[3]	Mice: Female 6-wk-old Balb/c mice are randomly divided into two groups (n = 10/group). The control group receives olive oil alone (vehicle) and the canthaxanthin-treated group receives canthaxanthin at a dose of 14 μg/kg body weight per day. At the end of the treatment, mice are killed by cervical dislocation and liver is excised, frozen in liquid nitrogen and stored at −80°C^[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Esatbeyoglu T, et al. Canthaxanthin: From molecule to function. Mol Nutr Food Res. 2017 Jun;61(6). [Content Brief] [2]. Huang DS, et al. Inhibitory effects of canthaxanthin on in vitro growth of murine tumor cells. Cancer Lett. 1992 Aug 31;65(3):209-13. [Content Brief] [3]. Palozza P, et al. Canthaxanthin supplementation alters antioxidant enzymes and iron concentration in liver of Balb/c mice. J Nutr. 2000 May;130(5):1303-8. [Content Brief] [4]. Chew BP, et al. A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res. 1999 May-Jun;19(3A):1849-53. [Content Brief] [5]. Grubbs CJ, et al. Effect of canthaxanthin on chemically induced mammary carcinogenesis. Oncology. 1991;48(3):239-45. [Content Brief]

Animal Administration
^[3]

Mice: Female 6-wk-old Balb/c mice are randomly divided into two groups (n = 10/group). The control group receives olive oil alone (vehicle) and the canthaxanthin-treated group receives canthaxanthin at a dose of 14 μg/kg body weight per day. At the end of the treatment, mice are killed by cervical dislocation and liver is excised, frozen in liquid nitrogen and stored at −80°C^[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

[1]. Esatbeyoglu T, et al. Canthaxanthin: From molecule to function. Mol Nutr Food Res. 2017 Jun;61(6). [Content Brief]

[2]. Huang DS, et al. Inhibitory effects of canthaxanthin on in vitro growth of murine tumor cells. Cancer Lett. 1992 Aug 31;65(3):209-13. [Content Brief]

[3]. Palozza P, et al. Canthaxanthin supplementation alters antioxidant enzymes and iron concentration in liver of Balb/c mice. J Nutr. 2000 May;130(5):1303-8. [Content Brief]

[4]. Chew BP, et al. A comparison of the anticancer activities of dietary beta-carotene, canthaxanthin and astaxanthin in mice in vivo. Anticancer Res. 1999 May-Jun;19(3A):1849-53. [Content Brief]

[5]. Grubbs CJ, et al. Effect of canthaxanthin on chemically induced mammary carcinogenesis. Oncology. 1991;48(3):239-45. [Content Brief]

Canthaxanthin 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液；该产品在溶液状态不稳定，建议您现用现配，即刻使用。

可选溶剂	浓度溶剂体积质量	1 mg	5 mg	10 mg	25 mg

Chloroform	1 mM	1.7704 mL	8.8521 mL	17.7041 mL	44.2603 mL
	5 mM	0.3541 mL	1.7704 mL	3.5408 mL	8.8521 mL
	10 mM	0.1770 mL	0.8852 mL	1.7704 mL	4.4260 mL
	15 mM	0.1180 mL	0.5901 mL	1.1803 mL	2.9507 mL
	20 mM	0.0885 mL	0.4426 mL	0.8852 mL	2.2130 mL
	25 mM	0.0708 mL	0.3541 mL	0.7082 mL	1.7704 mL
	30 mM	0.0590 mL	0.2951 mL	0.5901 mL	1.4753 mL
	40 mM	0.0443 mL	0.2213 mL	0.4426 mL	1.1065 mL

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Canthaxanthin514-78-3E 161g all-trans-Canthaxanthin角黄素斑蝥黄质斑蝥黄裸藻酮Reactive Oxygen SpeciesEndogenous MetaboliteInhibitorinhibitorinhibit

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Canthaxanthin (Synonyms: 斑蝥黄; E 161g; all-trans-Canthaxanthin)

Customer Review

Other Forms of Canthaxanthin:

MCE 顾客使用本产品发表的 2 篇科研文献